About CGH
  • Introduction
  • Chromosome Aberrations in Cancer
  • Comparative Genomic Hybridization (CGH) in Cancer Genomics
  • Array-based CGH
  • Quality Control in array-CGH
  • Applications of array-CGH
  • Future aspects
  • Reference
  • Resources (PDF)
    • Reference

    1. Mitelman F, Mertens F, Johansson B.
      A breakpoint map of recurrent chromosomal rearrangements in human neoplasia. Nat Genet. 1997 Apr;15 Spec No:417-74.
    2. Mitelman F, Johansson B, Mertens F.
      Fusion genes and rearranged genes as a linear function of chromosome aberrations in cancer. Nat Genet. 2004 Apr;36(4):331-4.
    3. Tsuruo T, Naito M, Tomida A, Fujita N, Mashima T, Sakamoto H, Haga N.
      Molecular targeting therapy of cancer: drug resistance, apoptosis and survival signal. Cancer Sci. 2003 Jan;94(1):15-21
    4. Hehlmann R.
      Current CML therapy: progress and dilemma. Leukemia. 2003 Jun;17(6):1010-2.
    5. Kallioniemi A, Kallioniemi OP, Sudar D, Rutovitz D, Gray JW, Waldman F, Pinkel D.
      Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors. Science. 1992 Oct 30;258(5083):818-21.
    6. Shayesteh L, Lu Y, Kuo WL, Baldocchi R, Godfrey T, Collins C, Pinkel D, Powell B, Mills GB, Gray JW.
      PIK3CA is implicated as an oncogene in ovarian cancer. Nat Genet. 1999 Jan;21(1):99-102.
    7. Collins C., Rommens J. M., Kowbel D., Godfrey T., Tanner M., Hwang S., Polikoff D., Nonet G., Cochran J., Myambo K., Jay K. E., Froula J., Cloutier T., Kuo W-L., Yaswen P., Dairkee S., Giovanola J., Hutchinson G. B., Isola J., Kallioniemi O-P., Palazzolo M., Martin C., Ericsson C., Pinkel D., Albertson D., Li W-B., Gray J. W.
      Positional cloning of ZNF217 and NABC1: genes amplified at 20q13.2 and overexpressed in breast carcinoma.. Proc. Natl. Acad. Sci. USA, 95: 8703-8708, 1998
    8. Sakabe T, Shinomiya T, Mori T, Ariyama Y, Fukuda Y, Fujiwara T, Nakamura Y, Inazawa J
      :Identification of a novel gene, MASL1, within an amplicon at 8p23.1 detected in malignant fibrous histiocytomas (MFH) by comparative genomic hybridization. Cancer Res51:511-15,1999.
    9. Tagawa H, Karnan S, Kasugai Y, Tuzuki S, Suzuki R, Hosokawa Y, Seto M.
      MASL1, a candidate oncogene found in amplification at 8p23.1, is translocated in immunoblastic B-cell lymphoma cell line OCI-LY8. Oncogene. 2004 Apr 1;23(14):2576-81.
    10. Imoto I, Tsuda H, Hirasawa A, Miura M, Sakamoto M, Hirohashi S, Inazawa J
      : Expression of cIAP1, a target for 11q22 amplification, correlates with resistance of cervical cancers to radiotherapy.Cancer Res 62:4860-6,2002
    11. Imoto I, Yang ZQ, Pimkhaokham A, Tsuda H, Shimada Y, Imamura M, Ohki M, Inazawa J
      :Identification of cIAP1 as a candidate target gene within an amplicon at 11q22 in esophageal squamous cell carcinomas.Cancer Res61:6629-34,2001.
    12. Saito-Ohara F, Imoto I, Inoue J, Hosoi H, Nakagawara A, Sugimoto T, Inazawa J:
      PPM1D is a potential target for 17q gain in neuroblastoma. Cancer Res 63:1876-83,2003.
    13. Hirasawa A, Saito-Ohara F, Inoue J, Aoki D, Susumu N, Yokoyama T, Nozawa S, Inazawa J, Imoto I
      : Association of 17q21-q24 Gain in Ovarian Clear Cell Adenocarcinomas with Poor Prognosis and Identification of PPM1D and APPBP2 as Likely Amplification Targets. Clin Cancer 9:1995-2004,2003.
    14. Yokoi S, Yasui K, Saito-Ohara F, Koshikawa K, Iizasa T, Fujisawa T, Terasaki T, Horii A, Takahashi T, Hirohashi S, Inazawa J
      : A novel target gene, SKP2, within the 5p13 amplicon that is frequently detected in small cell lung cancers. Am J Pathol 161:207-16,2002
    15. Yokoi S, Yasui K, Iizasa T, Takahashi T, Fujisawa T, Inazawa J.
      Down-regulation of SKP2 induces apoptosis in lung-cancer cells. Cancer Sci. 94:344-349,2003.
    16. Yokoi S, Yasui K, Mori M, Iizasa T, Fujisawa T, Inazawa J.
      SKP2 is amplified and over-expressed in non-small cell lung cancers, and its up-regulation is associated with lymph node metastasis.Am J Pathol 2004 (in press)
    17. Solinas-Toldo S, Lampel S, Stilgenbauer S, Nickolenko J, Benner A, Dohner H, Cremer T, Lichter P.
      Matrix-based comparative genomic hybridization: biochips to screen for genomic imbalances. Genes Chromosomes Cancer. 1997 Dec;20(4):399-407.
    18. Pinkel D, Segraves R, Sudar D, Clark S, Poole I, Kowbel D, Collins C, Kuo WL, Chen C, Zhai Y, Dairkee SH, Ljung BM, Gray JW, Albertson DG.
      High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays. Nat Genet. 1998 Oct;20(2):207-11.
    19. Pollack JR, Perou CM, Alizadeh AA, Eisen MB, Pergamenschikov A, Williams CF, Jeffrey SS, Botstein D, Brown PO.
      Genome-wide analysis of DNA copy-number changes using cDNA microarrays. Nat Genet. 1999 Sep;23(1):41-6.
    20. Veltman JA, Schoenmakers EF, Eussen BH, Janssen I, Merkx G, van Cleef B, van Ravenswaaij CM, Brunner HG, Smeets D, van Kessel AG.
      High-throughput analysis of subtelomeric chromosome rearrangements by use of array-based comparative genomic hybridization. Am J Hum Genet. 2002 May;70(5):1269-76. Epub 2002 Apr 09.
    21. Albertson DG, Pinkel D.
      Genomic microarrays in human genetic diseases and cancer. Hum Molecular Genet 12. 145-152,2003.
    22. Mantripragada KK, Buckley PG, de Stahl TD, Dumanski JP.
      Genomic microarrays in the spotlight.Trends Genet. 2004 Feb;20(2):87-94.
    23. Snijders AM, Nowak N, Segraves R, Blackwood S, Brown N, Conroy J, Hamilton G, Hindle AK, Huey B, Kimura K, Law S, Myambo K, Palmer J, Ylstra B, Yue JP, Gray JW, Jain AN, Pinkel D, Albertson DG.
      Assembly of microarrays for genome-wide measurement of DNA copy number. Nat Genet 29:263-4, 2001
    24. Ishkanian AS, Malloff CA, Watson SK, DeLeeuw RJ, Chi B, Coe BP, Snijders A, Albertson DG, Pinkel D, Marra MA, Ling V, MacAulay C, Lam WL.
      A tiling resolution DNA microarray with complete coverage of the human genome. Nat Genet. 2004 Mar;36(3):299-303. Epub 2004 Feb 15.
    25. Sonoda I, Imoto I, Inoue J, Shibata T, Shimada Y, Chin K, Imamura M, Amagasa T, Gray J, HirohashiS, Inazawa J.
      Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous-cell carcinoma
    26. Massion PP, Kuo WL, Stokoe D, Olshen AB, Treseler PA, Chin K, Chen C, Polikoff D, Jain AN, Pinkel D, Albertson DG, Jablons DM, Gray JW.
      Genomic copy number analysis of non-small cell lung cancer using array comparative genomic hybridization: implications of the phosphatidylinositol 3-kinase pathway. Cancer Res. 2002 Jul 1;62(13):3636-40.
    27. Veltman JA, Fridlyand J, Pejavar S, Olshen AB, Korkola JE, DeVries S, Carroll P, Kuo WL, Pinkel D, Albertson D, Cordon-Cardo C, Jain AN, Waldman FM.
      Array-based comparative genomic hybridization for genome-wide screening of DNA copy number in bladder tumors. Cancer Res. 2003 Jun 1;63(11):2872-80
    28. Barton K, Nucifora G.
      AML1 haploinsufficiency, gene dosage, and the predisposition to acute leukemia. Bioessays. 2000 Mar;22(3):214-8.
    29. Ren B, Robert F, Wyrick JJ, Aparicio O, Jennings EG, Simon I, Zeitlinger J, Schreiber J, Hannett N, Kanin E, Volkert TL, Wilson CJ, Bell SP, Young RA.
      Genome-wide location and function of DNA binding proteins. Science. 2000 Dec 22;290(5500):2306-9.
    30. Huang TH, Perry MR, Laux DE.
      Methylation profiling of CpG islands in human breast cancer cells. Hum Mol Genet. 1999 Mar;8(3):459-70.
    31. Gitan RS, Shi H, Chen CM, Yan PS, Huang TH.
      Methylation-specific oligonucleotide microarray: a new potential for high-throughput methylation analysis. Genome Res. 2002 Jan;12(1):158-64.
    32. Shi H, Maier S, Nimmrich I, Yan PS, Caldwell CW, Olek A, Huang TH.
      Oligonucleotide-based microarray for DNA methylation analysis: principles and applications. J Cell Biochem. 2003 Jan 1;88(1):138-43
    33. Locke DP, Segraves R, Carbone L, Archidiacono N, Albertson DG, Pinkel D, Eichler EE.
      Large-scale variation among human and great ape genomes determined by array comparative genomic hybridization. Genome Res. 2003 Mar;13(3):347-57.
    34. Toyota M, Ho C, Ahuja N, Jair KW, Li Q, Ohe-Toyota M, Baylin SB, Issa JP.
      Identification of differentially methylated sequences in colorectal cancer by methylated CpG island amplification. Cancer Res. 1999 May 15;59(10):2307-12.
    35. Bignell GR, Huang J, Greshock J, Watt S, Butler A, West S, Grigorova M, Jones KW, Wei W, Stratton MR, Futreal PA, Weber B, Shapero MH, Wooster R.
      High-resolution analysis of DNA copy number using oligonucleotide microarrays. Genome Res. 2004 Feb;14(2):287-95.
    36. Lucito R, Healy J, Alexander J, Reiner A, Esposito D, Chi M, Rodgers L, Brady A, Sebat J, Troge J, West JA, Rostan S, Nguyen KC, Powers S, Ye KQ, Olshen A, Venkatraman E, Norton L, Wigler M.
      Representational oligonucleotide microarray analysis: a high-resolution method to detect genome copy number variation. Genome Res. 2003 Oct;13(10):2291-305.
    37. Hatada I, Kato A, Morita S, Obata Y, Nagaoka K, Sakurada A, Sato M, Horii A, Tsujimoto A, Matsubara K.
      A microarray-based method for detecting methylated loci. J Hum Genet. 2002;47(8):448-51.
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