December 2011

The MCG CNV Database provides copy number variant ( CNV ) and loss of heterozygosity ( LOH ) detected through microarray analyses in healthy Japanese by our in-house BAC-based arrays, so-called MCG arrays1), and SNP array ( illumina, HumanOmniExpress Beadchip ). The MCG CNV Database shows an incidence of CNV and LOH in the Japanese healthy population and can be of assistance to estimate a pathogenicity of CNV or LOH detected in subjects having possible involvement of cryptic genomic aberrations behind their pathogenesis.


1) Inazawa J, Inoue J, Imoto I. Comparative genomic hybridization (CGH)-arrays pave the way for identification of novel cancer-related genes. 2004. Cancer Sci 95: 559-563.

Update History

Mar. 2011   CNV data by BAC arrays was released.
Dec. 2011   CNV and LOH data by SNP array were released.
Mar. 2013   Allele information of de novo CNV by SNP array was released.


  • Nobuyuki Hamajima, Professor
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine
  • Dr. Sueli Mieko Oba-Shinjo
    Laboratory of Molecular Biology, Department of Neurology, School of Medicine, São Paulo University, São Paulo, Brazil
  • Dr. Lucy Sayuri Ito
    Japanese Brazilian Health Professional Volunteer Group, São Paulo, Brazil

Contributors to the construction of this database are follows;

  • *Professor Johji Inazawa
  • Professor Issei Imoto
  • Dr. Shin Hayashi
  • Ms Ayako Takahashi
  • Ms Rumi Mori
  • Ms Daniela Tiaki Uehara
  • Ms Mitsuyo Naganawa

*Corresponding to this database

The construction of these databases was supported in part by
New Energy and Industrial Technology Development Organization ( NEDO ).

Contact us Human Genome Variation Database